articleTop 1% cited
Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives
Gut · 2011 · Vol. 60(5) · pp. 631–637
Marie Joossens✉(Universitair Ziekenhuis Leuven)Geert Huys(Ghent University Hospital)Margo Cnockaert(Ghent University Hospital)Vicky De PreterKristin VerbekePaul RutgeertsPeter Vandamme(Ghent University Hospital)Séverine Vermeire
Abstract
Unaffected relatives of patients with CD have a different composition of their microbiota compared with healthy controls. This dysbiosis is not characterised by lack of butyrate producing-bacteria as observed in CD but suggests a role for microorganisms with mucin degradation capacity.
Inflammatory Bowel DiseaseMicroscopic ColitisGut microbiota and healthRuminococcusDysbiosisFaecalibacterium prausnitziiGut floraMicrobiologyBifidobacteriumBiologyVeillonellaInternal medicineLactobacillus
MeSH terms
AdolescentAdultAgedAged, 80 and overBacteriaCrohn DiseaseDNA, BacterialFecesFemaleHumansMaleMiddle AgedSymbiosisCase-Control StudiesReverse Transcriptase Polymerase Chain Reaction
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References
Diversity of the human gastrointestinal tract microbiota revisited
Environmental Microbiology · 2007 · 552 citations
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Proceedings of the National Academy of Sciences · 2007 · 4,550 citations
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