article Open AccessTop 1% cited
Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults
PLoS ONE · 2010 · Vol. 5(2) · pp. e9085–e9085
Nadja Larsen✉(University of Copenhagen)Finn K. Vogensen(University of Copenhagen)Frans van den Berg(University of Copenhagen)Dennis Sandris Nielsen(University of Copenhagen)Anne Sofie Andreasen(Rigshospitalet)Bente Klarlund Pedersen(Rigshospitalet)Waleed Abu Al‐Soud(University of Copenhagen)Søren J. Sørensen(University of Copenhagen)Lars Hestbjerg Hansen(University of Copenhagen)Mogens Jakobsen(University of Copenhagen)
Abstract
The results of this study indicate that type 2 diabetes in humans is associated with compositional changes in intestinal microbiota. The level of glucose tolerance should be considered when linking microbiota with metabolic diseases such as obesity and developing strategies to control metabolic diseases by modifying the gut microbiota.
Gut microbiota and healthClostridium difficile and Clostridium perfringens researchDiet and metabolism studiesPrevotellaFirmicutesBacteroidesGut floraBacteroidetesType 2 diabetesBiologyBetaproteobacteriaClostridiaDiabetes mellitus
MeSH terms
AdultAgedBacteriaDiabetes Mellitus, Type 2DNA, BacterialFecesHumansIntestinesMaleMiddle AgedRNA, Ribosomal, 16SColony Count, MicrobialBody Mass IndexSequence Analysis, DNA
Funding
- Ministeriet for Fø devarer, Landbrug og Fiskeri
Citations
2,953
FWCI
37.73
field-weighted impact
References
39
Percentile
100%
vs. same field & year
Citations per year
Cited by
The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota
Hepatology · 2015 · 1,424 citations
Toward defining the autoimmune microbiome for type 1 diabetes
The ISME Journal · 2010 · 797 citations
Homeostasis of the gut barrier and potential biomarkers
American Journal of Physiology-Gastrointestinal and Liver Physiology · 2016 · 604 citations
Dietary Fibre Modulates the Gut Microbiota
Nutrients · 2021 · 599 citations
Microbes inside—from diversity to function: the case of <i>Akkermansia</i>
The ISME Journal · 2012 · 696 citations
Gut Microbiota in Cardiovascular Health and Disease
Circulation Research · 2017 · 1,620 citations
Proteobacteria: A Common Factor in Human Diseases
BioMed Research International · 2017 · 1,219 citations
Impacts of Gut Bacteria on Human Health and Diseases
International Journal of Molecular Sciences · 2015 · 1,026 citations
References
Obesity alters gut microbial ecology
Proceedings of the National Academy of Sciences · 2005 · 6,096 citations
Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR
Journal of Applied Microbiology · 2004 · 1,008 citations
Human colonic microbiota associated with diet, obesity and weight loss
International Journal of Obesity · 2008 · 1,220 citations
Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia
Diabetologia · 2007 · 1,744 citations
Inflammation, stress, and diabetes
Journal of Clinical Investigation · 2005 · 3,869 citations
The gut microbiota as an environmental factor that regulates fat storage
Proceedings of the National Academy of Sciences · 2004 · 6,132 citations
Quantification of<i>Bifidobacterium</i>spp.,<i>Escherichia coli</i>and<i>Clostridium difficile</i>in faecal samples of breast-fed and formula-fed infants by real-time PCR
FEMS Microbiology Letters · 2004 · 379 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.