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HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity

Current Biology · 2006 · Vol. 17(2) · pp. 165–172
Virginie ClémentPilar Sánchez‐GómezNicolas de TriboletIvan RadovanovicAriel Ruiz i Altaba
Hedgehog Signaling Pathway StudiesCancer-related Molecular PathwaysGenetics and Neurodevelopmental DisordersBiologyGLI1HedgehogStem cellCancer researchCancerCell biologyHedgehog signaling pathwayGliomaCancer stem cell

MeSH terms

Zinc Finger Protein GLI1AnimalsBrain NeoplasmsGliomaHumansTranscription FactorsNeoplastic Stem CellsSignal TransductionGene Expression Regulation, NeoplasticMiceHedgehog Proteins

Funding

  • Foundation for the National Institutes of Health
  • Louis-Jeantet Foundation
Citations
1,034
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