article Open AccessTop 1% cited
HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity
Current Biology · 2006 · Vol. 17(2) · pp. 165–172
Virginie Clément✉(University of Geneva)Pilar Sánchez‐Gómez(University of Geneva)Nicolas de Tribolet(University Hospital of Geneva)Ivan Radovanovic(University Hospital of Geneva)Ariel Ruiz i Altaba(University of Geneva)
Hedgehog Signaling Pathway StudiesCancer-related Molecular PathwaysGenetics and Neurodevelopmental DisordersBiologyGLI1HedgehogStem cellCancer researchCancerCell biologyHedgehog signaling pathwayGliomaCancer stem cell
MeSH terms
Zinc Finger Protein GLI1AnimalsBrain NeoplasmsGliomaHumansTranscription FactorsNeoplastic Stem CellsSignal TransductionGene Expression Regulation, NeoplasticMiceHedgehog Proteins
Funding
- Foundation for the National Institutes of Health
- Louis-Jeantet Foundation
Citations
1,034
FWCI
21.72
field-weighted impact
References
65
Percentile
100%
vs. same field & year
Citations per year
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References
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Nature Medicine · 2001 · 2,273 citations
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Cell · 2005 · 4,462 citations
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
Nature Genetics · 2006 · 2,442 citations
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
Cancer Cell · 2006 · 3,167 citations
Sonic hedgehog regulates the growth and patterning of the cerebellum
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