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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

Cancer Cell · 2006 · Vol. 9(3) · pp. 157–173
Heidi PhillipsSamir KharbandaRuihuan ChenWilliam F. ForrestRobert SorianoThomas D. WuAnjan MisraJanice NigroHoward ColmanLiliana SoroceanuP. Mickey WilliamsZora ModrušanBurt G. FeuersteinKen Aldape
Glioma Diagnosis and TreatmentMicroRNA in disease regulationNeurogenesis and neuroplasticity mechanismsBiologyNeurogenesisLineage markersPTENGliomaCancer researchNeural stem cellAngiogenesisMesenchymeAstrocytoma

MeSH terms

BrainBrain NeoplasmsGliomaHumansMembrane ProteinsNeoplasm InvasivenessPrognosisBiomarkers, TumorGene ExpressionGene Expression Regulation, NeoplasticPolymerase Chain ReactionIn Situ HybridizationDisease ProgressionGene DosageOligonucleotide Array Sequence Analysis

Funding

  • Cedars-Sinai Medical Center
  • University of California, San Francisco
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