reviewTop 1% cited

Hedgehog Signaling in Development and Cancer

Developmental Cell · 2008 · Vol. 15(6) · pp. 801–812

Jin Jiang✉(The University of Texas Southwestern Medical Center)Chi-chung Hui(University of Toronto)

Hedgehog Signaling Pathway Studies Epigenetics and DNA Methylation Tumors and Oncological CasesBiologyHedgehogCancerHedgehog signaling pathwaySignal transductionCancer researchCell biologyComputational biologyGenetics

MeSH terms

AnimalsCell DifferentiationDrosophilaHumansModels, BiologicalNeoplasmsNeuronsStem CellsSignal TransductionGene Expression Regulation, NeoplasticGene Expression Regulation, DevelopmentalCell ProliferationHedgehog Proteins

Funding

Leukemia and Lymphoma Society
National Institutes of Health
National Cancer Institute

Citations

1,075

FWCI

33.10

field-weighted impact

References

148

Percentile

100%

vs. same field & year

Citations per year

Cited by

Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks

Journal of Clinical Medicine · 2016 · 313 citations

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

Trends in Pharmacological Sciences · 2009 · 644 citations

References

Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function

PLoS Genetics · 2005 · 911 citations

Hedgehog signaling in animal development: paradigms and principles

Genes & Development · 2001 · 2,990 citations

HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity

Current Biology · 2006 · 1,034 citations

The Graded Response to Sonic Hedgehog Depends on Cilia Architecture

Developmental Cell · 2007 · 750 citations

Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.