reviewTop 1% cited
Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
Nature Neuroscience · 2010 · Vol. 13(7) · pp. 812–818
Jorge J. Palop✉(University of California, San Francisco)Lennart Mucke(University of California, San Francisco)
Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNeuroscienceExcitatory postsynaptic potentialInhibitory postsynaptic potentialNeurotransmissionRegulatorMechanism (biology)DiseaseAmyloid (mycology)Alzheimer's diseaseDementia
MeSH terms
Alzheimer DiseaseHumansNeural PathwaysSynaptic TransmissionSynapsesAmyloid beta-Peptides
Funding
- National Institutes of Health
Citations
1,621
FWCI
42.38
field-weighted impact
References
77
Percentile
100%
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Citations per year
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References
High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation
Journal of Neuroscience · 2000 · 1,860 citations
Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum?
Trends in Neurosciences · 2001 · 994 citations
Regulation of NMDA receptor trafficking by amyloid-β
Nature Neuroscience · 2005 · 1,544 citations
Aβ Oligomers – a decade of discovery
Journal of Neurochemistry · 2007 · 1,905 citations
Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease
JAMA · 1997 · 4,580 citations
Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway
Journal of Neuroscience · 2007 · 1,574 citations
Incidence and Predictors of Seizures in Patients with Alzheimer's Disease
Epilepsia · 2006 · 592 citations
Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
Annals of Neurology · 1991 · 4,370 citations
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