reviewTop 1% cited

The amyloid state and its association with protein misfolding diseases

Nature Reviews Molecular Cell Biology · 2014 · Vol. 15(6) · pp. 384–396

Tuomas P. J. Knowles✉(University of Cambridge)Michele Vendruscolo(University of Cambridge)Christopher M. Dobson(University of Cambridge)

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Alzheimer's disease research and treatments Endoplasmic Reticulum Stress and Disease Protein Structure and DynamicsAmyloid (mycology)Protein aggregationDiseaseProtein foldingBiochemistry of Alzheimer's diseaseAmyloid fibrilNeuroscienceBiologyMedicineAmyloid precursor protein

MeSH terms

Alzheimer DiseaseAmyloidAmyloidosisAnimalsHumansProtein ConformationProtein Folding

Funding

Frances and Augustus Newman Foundation
Biotechnology and Biological Sciences Research Council

Citations

2,362

FWCI

101.38

field-weighted impact

References

185

Percentile

100%

vs. same field & year

Citations per year

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References

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide

Nature Reviews Molecular Cell Biology · 2007 · 4,679 citations

Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway

Journal of Neuroscience · 2007 · 1,574 citations

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

Nature Chemistry · 2009 · 908 citations

Protein aggregation and neurodegenerative disease

Nature Medicine · 2004 · 3,433 citations

Intrinsically unstructured proteins and their functions

Nature Reviews Molecular Cell Biology · 2005 · 3,843 citations

From Levinthal to pathways to funnels

Nature Structural & Molecular Biology · 1997 · 2,305 citations

The amyloid state and its association with protein misfolding diseases

Nature Reviews Molecular Cell Biology · 2014 · 2,362 citations

Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade

Annual Review of Biochemistry · 2017 · 2,604 citations

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