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New insights on the role of microglia in synaptic pruning in health and disease

Current Opinion in Neurobiology · 2015 · Vol. 36 · pp. 128–134

Soyon Hong(Boston Children's Hospital)Lasse Dissing‐Olesen(Boston Children's Hospital)Beth Stevens✉(Boston Children's Hospital)

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Neuroinflammation and Neurodegeneration Mechanisms Neurological Disease Mechanisms and Treatments Nuclear Receptors and SignalingSynaptic pruningMicrogliaNeurosciencePruningDiseasePsychologyBiologyMedicineImmunologyInflammation

Funding

Alzheimer's Research Trust
Lundbeckfonden
National Institutes of Health

Citations

578

FWCI

26.59

field-weighted impact

References

81

Percentile

100%

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Citations per year

References

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Neuron · 2007 · 1,667 citations

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Neuron · 2012 · 3,978 citations

Microglia Modulate Wiring of the Embryonic Forebrain

Cell Reports · 2014 · 663 citations

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New insights on the role of microglia in synaptic pruning in health and disease · Scinovex