article Open AccessTop 10% cited
Suppression of SHP-2 and ERK Signalling Promotes Self-Renewal of Mouse Embryonic Stem Cells
Developmental Biology · 1999 · Vol. 210(1) · pp. 30–43
Tom Burdon✉(University of Edinburgh)Craig Stracey(University of Edinburgh)Ian Chambers(University of Edinburgh)Jennifer Nichols(University of Edinburgh)Austin Smith(University of Edinburgh)
Cytokine Signaling Pathways and InteractionsPluripotent Stem Cells ResearchSignaling Pathways in DiseaseBiologyGlycoprotein 130Cell biologyEmbryonic stem cellMAPK/ERK pathwayProtein tyrosine phosphataseStem cellCytokine receptorInduced pluripotent stem cellCytokine
MeSH terms
AnimalsCell DifferentiationCell DivisionCells, CulturedChimeraDNA-Binding ProteinsEnzyme ActivationFlavonoidsMembrane GlycoproteinsMutationStem CellsSuppression, GeneticTransfectionTyrosineSignal Transduction
Funding
- Directorate for Biological Sciences
- Chugai Pharmaceutical
- Biotechnology and Biological Sciences Research Council
Citations
570
FWCI
3.83
field-weighted impact
References
75
Percentile
94%
vs. same field & year
Citations per year
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References
Establishment in culture of pluripotential cells from mouse embryos
Nature · 1981 · 8,538 citations
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.
Proceedings of the National Academy of Sciences · 1981 · 5,698 citations
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
Genes & Development · 1998 · 1,530 citations
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