article Open AccessTop 1% cited
Maintaining remission of ulcerative colitis with the probiotic <i>Escherichia coli</i> Nissle 1917 is as effective as with standard mesalazine
Gut · 2004 · Vol. 53(11) · pp. 1617–1623
Wolfgang Kruis✉(TH Köln - University of Applied Sciences)P Frič(Military University Hospital Prague)J Pokrotnieks(Pauls Stradiņš Clinical University Hospital)M Lukáš(Charles University)B Fixa(Charles University)M Kaščák(Vysoká škola manažmentu, City University of Seattle)M A Kamm(St Mark's Hospital)J Weismueller(Koblenz University of Applied Sciences)C Beglinger(University Hospital of Basel)M Stolte(Bayreuth Medical Center)C Wolff(Ardeypharm (Germany))J Schulze(Ardeypharm (Germany))
Abstract
The probiotic drug E coli Nissle 1917 shows efficacy and safety in maintaining remission equivalent to the gold standard mesalazine in patients with ulcerative colitis. The effectiveness of probiotic treatment further underlines the pathogenetic significance of the enteric flora.
Probiotics and Fermented FoodsGut microbiota and healthDigestive system and related healthMesalazineUlcerative colitisProbioticTolerabilityMedicineInternal medicineGastroenterologyGroup BInflammatory bowel diseaseColitis
MeSH terms
AdultAgedAged, 80 and overAnti-Inflammatory Agents, Non-SteroidalColitis, UlcerativeDouble-Blind MethodEscherichia coliFemaleHumansMaleMiddle AgedRecurrenceRemission InductionMesalamineProbiotics
Funding
- Univerzita Komenského v Bratislave
- Karolinska Institutet
Citations
1,253
FWCI
80.03
field-weighted impact
References
44
Percentile
100%
vs. same field & year
Citations per year
Cited by
The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation
Nutrients · 2018 · 570 citations
Encapsulation of probiotic living cells: From laboratory scale to industrial applications
Journal of Food Engineering · 2011 · 852 citations
An overview of the last advances in probiotic and prebiotic field
LWT · 2012 · 512 citations
The gut microbiota and host health: a new clinical frontier
Gut · 2015 · 2,277 citations
Efficacy of <i>Lactobacillus</i> GG in maintaining remission of ulcerative colitis
Alimentary Pharmacology & Therapeutics · 2006 · 467 citations
Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation
World Journal of Gastroenterology · 2018 · 637 citations
Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria
World Journal of Gastroenterology · 2007 · 424 citations
Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body
Frontiers in Immunology · 2021 · 821 citations
References
Double‐blind comparison of an oral <i>Escherichia coli</i> preparation and mesalazine in maintaining remission of ulcerative colitis
Alimentary Pharmacology & Therapeutics · 1997 · 763 citations
Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis
Alimentary Pharmacology & Therapeutics · 1999 · 564 citations
Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial
Gastroenterology · 2000 · 1,484 citations
Saccharomyces boulardii in Maintenance Treatment of Crohn’s Disease
Digestive Diseases and Sciences · 2000 · 713 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.