reviewTop 1% cited
Functions of DNA methylation: islands, start sites, gene bodies and beyond
Nature Reviews Genetics · 2012 · Vol. 13(7) · pp. 484–492
Peter A. Jones✉(University of Southern California)
Epigenetics and DNA MethylationRNA modifications and cancerGenomics and Chromatin DynamicsDNA methylationBiologyEpigenetics of physical exerciseRNA-Directed DNA MethylationEpigeneticsEpigenomicsGeneticsCpG siteIllumina Methylation AssayMethylation
MeSH terms
Gene Expression RegulationGenesModels, MolecularRepetitive Sequences, Nucleic AcidCpG IslandsDNA MethylationTranscription Initiation SiteRegulatory Elements, Transcriptional
Funding
- National Institutes of Health
Citations
6,155
FWCI
133.16
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101
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100%
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References
Dynamic changes in the human methylome during differentiation
Genome Research · 2010 · 1,023 citations
Cytosine methylation and the ecology of intragenomic parasites
Trends in Genetics · 1997 · 1,928 citations
A decade of exploring the cancer epigenome — biological and translational implications
Nature reviews. Cancer · 2011 · 2,835 citations
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Cell · 1999 · 6,039 citations
Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
Cancer Cell · 2010 · 2,713 citations
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
Nature Genetics · 2009 · 2,237 citations
Chromatin organization marks exon-intron structure
Nature Structural & Molecular Biology · 2009 · 635 citations
CpG islands – ‘A rough guide’
FEBS Letters · 2009 · 883 citations
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