article Open AccessTop 1% cited
Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
Cancer Cell · 2014 · Vol. 26(4) · pp. 577–590
Xiaojing Yang✉(University of Southern California)Han Han(University of Southern California)Daniel D. De Carvalho(Princess Margaret Cancer Centre)Fides D. Lay(University of Southern California)Peter A. Jones(University of Southern California)Gangning Liang(University of Southern California)
Epigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancerDNA methylationMethylationBiologyGenePromoterGene expressionEpigeneticsCarcinogenesisRegulation of gene expressionEpigenetics of physical exercise
MeSH terms
Cell DivisionColonic NeoplasmsHumansPromoter Regions, GeneticGene ExpressionDNA Methylation
Funding
- Princess Margaret Cancer Foundation
- National Institutes of Health
- National Cancer Institute
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References
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A decade of exploring the cancer epigenome — biological and translational implications
Nature reviews. Cancer · 2011 · 2,835 citations
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Cancer Cell · 2012 · 3,226 citations
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Cancer · 2006 · 1,506 citations
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Cell · 2011 · 65,668 citations
Functions of DNA methylation: islands, start sites, gene bodies and beyond
Nature Reviews Genetics · 2012 · 6,155 citations
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