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DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGS
Annual Review of Biochemistry · 1989 · Vol. 58(1) · pp. 351–375
Leroy F. Liu✉(Johns Hopkins University)
Abstract
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More
Biotechnology and Related FieldsHippo pathway signaling and YAP/TAZDrosophila melanogasterRegulatorBiologyCell biologyTopoisomeraseDNAHippo signaling pathwayCell fate determinationCell growthComputational biology
MeSH terms
AnimalsAnti-Infective AgentsAntineoplastic AgentsDNA, NeoplasmDrug ResistanceHumansMammals4-QuinolonesTopoisomerase I Inhibitors
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