article Open AccessTop 1% cited
Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
Cell Metabolism · 2007 · Vol. 5(6) · pp. 415–425
Takeshi Inagaki✉(The University of Texas Southwestern Medical Center)Paul A. Dutchak(The University of Texas Southwestern Medical Center)Guixiang Zhao(The University of Texas Southwestern Medical Center)Xunshan Ding(Howard Hughes Medical Institute)Laurent Gautron(The University of Texas Southwestern Medical Center)Vinay Parameswara(The University of Texas Southwestern Medical Center)Yong Li(Van Andel Institute)Regina Goetz(New York University)Moosa Mohammadi(New York University)Victoria Esser(The University of Texas Southwestern Medical Center)Joel K. Elmquist(The University of Texas Southwestern Medical Center)Robert D. Gerard(The University of Texas Southwestern Medical Center)Shawn C. Burgess(Southwestern Medical Center)Robert E. Hammer(The University of Texas Southwestern Medical Center)David J. Mangelsdorf(Howard Hughes Medical Institute)Steven A. Kliewer(The University of Texas Southwestern Medical Center)
Fibroblast Growth Factor ResearchPeroxisome Proliferator-Activated ReceptorsAdipose Tissue and MetabolismEndocrine systemEndocrinologyFGF21Fibroblast growth factorInternal medicinePeroxisome proliferator-activated receptorFibroblastMedicineHormoneCell biology
MeSH terms
AdenoviridaeAdipose TissueAnimalsCells, CulturedFastingFemaleFibroblast Growth FactorsHumansLipolysisLiverMaleMice, Inbred C57BLMice, TransgenicPlasmidsRNA, Messenger
Funding
- University of Texas Southwestern Medical Center
- National Institutes of Health
Citations
1,480
FWCI
21.45
field-weighted impact
References
57
Percentile
100%
vs. same field & year
Citations per year
Cited by
Therapeutic potential of FGF21 in diabetes
Journal of Medicinal Plants Studies · 2017 · 4 citations
Fibroblast Growth Factor 21 as an emerging metabolic regulator: clinical perspectives
Clinical Endocrinology · 2012 · 294 citations
Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse
Molecular Endocrinology · 2010 · 677 citations
Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy
American Journal of Physiology-Gastrointestinal and Liver Physiology · 2020 · 440 citations
Fibroblast Growth Factor 21 Corrects Obesity in Mice
Endocrinology · 2008 · 1,010 citations
Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
Diabetes · 2008 · 1,133 citations
Ketone body metabolism and cardiovascular disease
American Journal of Physiology-Heart and Circulatory Physiology · 2013 · 442 citations
Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation
Cell Metabolism · 2009 · 1,100 citations
References
FGF-21 as a novel metabolic regulator
Journal of Clinical Investigation · 2005 · 2,064 citations
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
Cell Metabolism · 2005 · 1,777 citations
Evolution of the Fgf and Fgfr gene families
Trends in Genetics · 2004 · 1,084 citations
1α,25-Dihydroxyvitamin D<sub>3</sub>upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport
American Journal of Physiology-Gastrointestinal and Liver Physiology · 2005 · 405 citations
Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting
Journal of Clinical Investigation · 1999 · 1,632 citations
The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21
Endocrinology · 2006 · 731 citations
Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States
Cell Metabolism · 2007 · 1,463 citations
A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES
Journal of Biological Chemistry · 1957 · 64,580 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.