article Open AccessTop 1% cited
Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States
Cell Metabolism · 2007 · Vol. 5(6) · pp. 426–437
Michael K. Badman(Beth Israel Deaconess Medical Center)Pavlos Pissios(Beth Israel Deaconess Medical Center)Adam R. Kennedy(Beth Israel Deaconess Medical Center)Γεώργιος Κούκος(Boston University)Jeffrey S. Flier(Beth Israel Deaconess Medical Center)Eleftheria Maratos–Flier✉(Beth Israel Deaconess Medical Center)
Fibroblast Growth Factor ResearchKruppel-like factors researchLipid metabolism and disordersFGF21KetogenesisEndocrinologyInternal medicineKetone bodiesLipid metabolismFGF19RegulatorBiologyFibroblast growth factor
MeSH terms
AdenoviridaeAnimalsHypolipidemic AgentsCells, CulturedFibroblast Growth FactorsGene Expression RegulationKetosisLiverMaleMice, Inbred C57BLFenofibrateRNA, MessengerTransfectionImmunoblottingMice, Knockout
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References
FGF-21 as a novel metabolic regulator
Journal of Clinical Investigation · 2005 · 2,064 citations
Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting
Journal of Clinical Investigation · 1999 · 1,632 citations
Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
Cell Metabolism · 2007 · 1,480 citations
The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21
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Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
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