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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

Cell Metabolism · 2005 · Vol. 2(4) · pp. 217–225

Takeshi Inagaki✉(The University of Texas Southwestern Medical Center)Mihwa Choi(The University of Texas Southwestern Medical Center)Antonio Moschetta(Howard Hughes Medical Institute)Li Peng(The University of Texas Southwestern Medical Center)Carolyn L. Cummins(Howard Hughes Medical Institute)Jeffrey G. McDonald(The University of Texas Southwestern Medical Center)Guizhen Luo(Research Triangle Park Foundation)Stacey A. Jones(Research Triangle Park Foundation)Bryan Goodwin(Research Triangle Park Foundation)James A. Richardson(The University of Texas Southwestern Medical Center)Robert D. Gerard(The University of Texas Southwestern Medical Center)Joyce J. Repa(The University of Texas Southwestern Medical Center)David J. Mangelsdorf(Howard Hughes Medical Institute)Steven A. Kliewer(The University of Texas Southwestern Medical Center)

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Pancreatitis Pathology and Treatment Pediatric Hepatobiliary Diseases and Treatments Drug Transport and Resistance MechanismsEnterohepatic circulationHomeostasisFGF19Bile acidFibroblast growth factorCell biologyFGF21Iron homeostasisBiologyChemistry

MeSH terms

Receptor, Farnesoid X-ActivatedAnimalsBile Acids and SaltsCholesterol 7-alpha-HydroxylaseCloning, MolecularDNA-Binding ProteinsEnterohepatic CirculationEpitheliumFibroblast Growth FactorsHomeostasisHumansIntestinal MucosaIntestinesLiverMale

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Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse