reviewTop 1% cited

Protein aggregation and neurodegenerative disease

Nature Medicine · 2004 · Vol. 10(S7) · pp. S10–S17

Christopher A. Ross✉(Johns Hopkins Medicine)Michelle A. Poirier(Johns Hopkins Medicine)

Alzheimer's disease research and treatments Prion Diseases and Protein Misfolding Genetic Neurodegenerative DiseasesPathogenesisProtein aggregationDiseaseAmyotrophic lateral sclerosisProtein foldingAmyloid (mycology)BiologyAggresomeInclusion bodiesCell biology

MeSH terms

Huntingtin ProteinAnimalsInclusion BodiesHumansModels, BiologicalNerve Tissue ProteinsNuclear ProteinsPeptidesAmyloid beta-PeptidesProtein Structure, SecondaryProtein FoldingNeurodegenerative DiseasesUbiquitinMice

Funding

National Institute of Neurological Disorders and Stroke

Citations

3,433

FWCI

53.59

field-weighted impact

References

130

Percentile

100%

vs. same field & year

Citations per year

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References

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Science · 2002 · 13,715 citations

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Annual Review of Biochemistry · 1997 · 1,649 citations

P<scp>ROTOFIBRILS</scp>, P<scp>ORES</scp>, F<scp>IBRILS, AND</scp> N<scp>EURODEGENERATION</scp>: Separating the Responsible Protein Aggregates from The Innocent Bystanders

Annual Review of Neuroscience · 2003 · 1,643 citations

Soluble pool of A? amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

Annals of Neurology · 1999 · 1,797 citations

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