article Open AccessTop 1% cited
AMP-Activated Protein Kinase Induces a p53-Dependent Metabolic Checkpoint
Molecular Cell · 2005 · Vol. 18(3) · pp. 283–293
Russell G. Jones✉(Cancer Research Institute)David R. Plas(Cancer Research Institute)Sara Kubek(Cancer Research Institute)Monica Buzzai(Cancer Research Institute)James Mu(Howard Hughes Medical Institute)Yang Xu(University of California San Diego)Morris J. Birnbaum(Howard Hughes Medical Institute)Craig B. Thompson(Cancer Research Institute)
Cancer-related Molecular PathwaysMetabolism, Diabetes, and CancerAutophagy in Disease and TherapyAMPKCell biologyBiologyAMP-activated protein kinaseCell cycle checkpointCell cycleProtein kinase ACHEK1PhosphorylationCell growth
MeSH terms
AnimalsCell CycleCell LineCell SurvivalFibroblastsGlucoseHumansMultienzyme ComplexesPhosphorylationSerineTumor Suppressor Protein p53Cellular SenescenceProtein Serine-Threonine KinasesCell ProliferationMice
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References
LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
Current Biology · 2003 · 1,631 citations
WAF1, a potential mediator of p53 tumor suppression
Cell · 1993 · 8,369 citations
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
Nature Cell Biology · 2003 · 1,087 citations
The AMP-activated protein kinase cascade – a unifying system for energy control
Trends in Biochemical Sciences · 2003 · 1,112 citations
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