review Open AccessTop 1% cited
The P53 pathway: what questions remain to be explored?
Cell Death and Differentiation · 2006 · Vol. 13(6) · pp. 1027–1036
Arnold J. Levine✉(Institute for Advanced Study)Wenwei Hu(Rutgers Cancer Institute of New Jersey)Zhaohui Feng(Princeton University)
Cancer-related Molecular PathwaysUbiquitin and proteasome pathwaysEpigenetics and DNA MethylationDNA damageSignal transductionBiologyOrganismGeneCell biologyGadd45Cell cycleSenescenceCell cycle checkpoint
MeSH terms
AnimalsCell Transformation, NeoplasticDNAHumansMutationTranscription, GeneticSignal TransductionTumor Suppressor Protein p53Cell Cycle ProteinsProtein IsoformsResponse ElementsApoptosis Regulatory ProteinsProto-Oncogene Proteins c-mdm2
Citations
661
FWCI
23.46
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References
83
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100%
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References
Post‐translational modifications and activation of p53 by genotoxic stresses
European Journal of Biochemistry · 2001 · 1,073 citations
Decision making by p53: life, death and cancer
Cell Death and Differentiation · 2003 · 1,075 citations
The p53 pathway: positive and negative feedback loops
Oncogene · 2005 · 1,985 citations
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
Current Opinion in Cell Biology · 2003 · 740 citations
AMP-Activated Protein Kinase Induces a p53-Dependent Metabolic Checkpoint
Molecular Cell · 2005 · 1,582 citations
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