article Open AccessTop 1% cited
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
Nature Cell Biology · 2003 · Vol. 5(8) · pp. 741–747
Simona Parrinello✉(Lawrence Berkeley National Laboratory)Enrique Samper(Buck Institute for Research on Aging)Ana Krtolica(Lawrence Berkeley National Laboratory)Joshua C. Goldstein(Lawrence Berkeley National Laboratory)Simon Melov(Buck Institute for Research on Aging)Judith Campisi(Lawrence Berkeley National Laboratory)
Telomeres, Telomerase, and SenescenceDNA Repair MechanismsSingle-cell and spatial transcriptomicsDNA damageBiologyTelomereSenescenceReactive oxygen speciesCell biologyEmbryonic stem cellFibroblastOxygenMolecular biology
MeSH terms
AnimalsCell DivisionCells, CulturedDNA DamageDNA RepairFibroblastsHumansMice, Inbred BALB CMice, Inbred C57BLOxygenCellular SenescenceComet AssayMice
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Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA
Carcinogenesis · 1993 · 820 citations
QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES
The Journal of Cell Biology · 1963 · 2,748 citations
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