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Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study
Archives of Surgery · 2011 · Vol. 147(2) · pp. 113–113
Jonathan J. Morrison✉(United States Army Institute of Surgical Research)
Abstract
The use of TXA with blood component-based resuscitation following combat injury results in improved measures of coagulopathy and survival, a benefit that is most prominent in patients requiring massive transfusion. Treatment with TXA should be implemented into clinical practice as part of a resuscitation strategy following severe wartime injury and hemorrhage.
Trauma, Hemostasis, Coagulopathy, ResuscitationTrauma and Emergency Care StudiesBlood transfusion and managementMedicineTranexamic acidCoagulopathyPacked red blood cellsInjury Severity ScoreBlood transfusionResuscitationOdds ratioBlood productRetrospective cohort study
MeSH terms
AdolescentAdultAntifibrinolytic AgentsBlast InjuriesBlood TransfusionClinical ProtocolsFemaleHumansMaleMilitary MedicineMilitary PersonnelResuscitationRetrospective StudiesShock, HemorrhagicTranexamic Acid
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Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study
Archives of Surgery · 2011 · 785 citations
References
Injury Severity and Causes of Death From Operation Iraqi Freedom and Operation Enduring Freedom: 2003–2004 Versus 2006
The Journal of Trauma: Injury, Infection, and Critical Care · 2008 · 613 citations
A Revision of the Trauma Score
The Journal of Trauma: Injury, Infection, and Critical Care · 1989 · 1,922 citations
Acute Coagulopathy of Trauma: Hypoperfusion Induces Systemic Anticoagulation and Hyperfibrinolysis
The Journal of Trauma: Injury, Infection, and Critical Care · 2008 · 726 citations
The Ratio of Blood Products Transfused Affects Mortality in Patients Receiving Massive Transfusions at a Combat Support Hospital
The Journal of Trauma: Injury, Infection, and Critical Care · 2007 · 1,580 citations
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study
Archives of Surgery · 2011 · 785 citations
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