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A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

New England Journal of Medicine · 2004 · Vol. 351(27) · pp. 2817–2826
Soonmyung PaikSteven ShakGong TangChungyeul KimJoffre BakerMaureen CroninFrederick L. BaehnerMichael G. WalkerDrew WatsonTaesung ParkW. Douglas B. HillerEdwin R. FisherD. Lawrence WickerhamJohn BryantNorman Wolmark

Abstract

The recurrence score has been validated as quantifying the likelihood of distant recurrence in tamoxifen-treated patients with node-negative, estrogen-receptor-positive breast cancer.

Breast Cancer Treatment StudiesHER2/EGFR in Cancer ResearchEstrogen and related hormone effectsMedicineConfidence intervalBreast cancerInternal medicineOncologyTamoxifenProportional hazards modelRelative riskCancerEstrogen receptor

MeSH terms

AlgorithmsBreast NeoplasmsDNA, NeoplasmEstrogen AntagonistsFemaleFollow-Up StudiesHumansLymphatic MetastasisMiddle AgedNeoplasm MetastasisPrognosisReceptors, EstrogenReceptors, ProgesteroneRecurrenceRisk
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