article Open AccessTop 1% cited
Hypoxia Requires Notch Signaling to Maintain the Undifferentiated Cell State
Developmental Cell · 2005 · Vol. 9(5) · pp. 617–628
Maria Gustafsson✉(Karolinska Institutet)Xiaowei Zheng(Karolinska Institutet)Teresa Pereira(Karolinska Institutet)Katarina Gradin(Karolinska Institutet)Shaobo Jin(Karolinska Institutet)Johan Lundkvist(Karolinska Institutet)Jorge L. Ruas(Karolinska Institutet)Lorenz Poellinger(Karolinska Institutet)Urban Lendahl(Karolinska Institutet)Maria Bondesson(Karolinska Institutet)
Cancer, Hypoxia, and MetabolismEpigenetics and DNA MethylationDevelopmental Biology and Gene RegulationNotch signaling pathwayBiologyCell biologyErythropoiesisAngiogenesisRegulatorCellular differentiationCell fate determinationStem cellHypoxia (environmental)
MeSH terms
Transcription Factor HES-1AnimalsHypoxiaCarbamatesCell DifferentiationCell LineDipeptidesRepressor ProteinsStem CellsSignal TransductionHomeodomain ProteinsMyoblastsCell Line, TumorMiceBasic Helix-Loop-Helix Proteins
Funding
- McKnight Foundation
Citations
1,098
FWCI
18.57
field-weighted impact
References
56
Percentile
99%
vs. same field & year
Citations per year
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References
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
Genes & Development · 2002 · 1,520 citations
Notch Signaling: From the Outside In
Developmental Biology · 2000 · 980 citations
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
Nature Cell Biology · 2000 · 1,582 citations
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