review Open AccessTop 1% cited
The role of hypoxia-inducible factors in tumorigenesis
Cell Death and Differentiation · 2008 · Vol. 15(4) · pp. 678–685
Erinn B. Rankin✉(Stanford University)Amato J. Giaccia(Stanford University)
Cancer, Hypoxia, and MetabolismCancer-related Molecular PathwaysNeuroblastoma Research and TreatmentsAngiogenesisRegulatorCarcinogenesisCellular adaptationTranscription factorBiologyCancer researchErythropoiesisHypoxia-inducible factorsCell growth
MeSH terms
Endothelial PAS Domain-Containing Protein 1Adaptation, PhysiologicalAnimalsHypoxiaCell DifferentiationEnergy MetabolismHumansNeoplasm InvasivenessNeoplasm MetastasisNeoplasmsNeovascularization, PathologicOxygenSignal TransductionCell HypoxiaCell Proliferation
Citations
794
FWCI
24.98
field-weighted impact
References
105
Percentile
100%
vs. same field & year
Citations per year
Cited by
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References
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Nature · 2000 · 8,970 citations
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American Journal of Physiology-Cell Physiology · 1996 · 1,209 citations
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
Nature Medicine · 2004 · 2,582 citations
Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
Molecular and Cellular Biology · 2005 · 929 citations
HIF-1 and mechanisms of hypoxia sensing
Current Opinion in Cell Biology · 2001 · 1,266 citations
Purification and Characterization of Hypoxia-inducible Factor 1
Journal of Biological Chemistry · 1995 · 2,061 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
American Journal Of Pathology · 2000 · 1,298 citations
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