article Open AccessTop 1% cited
Basal-Like Breast Cancer Defined by Five Biomarkers Has Superior Prognostic Value than Triple-Negative Phenotype
Clinical Cancer Research · 2008 · Vol. 14(5) · pp. 1368–1376
Maggie C.U. Cheang✉(Vancouver Coastal Health Research Institute)David Voduc(Vancouver Coastal Health Research Institute)Chris Bajdik(BC Cancer Agency)Samuel Leung(University of British Columbia)Steven McKinney(BC Cancer Agency)Stephen Chia(BC Cancer Agency)Charles M. Perou(University of North Carolina at Chapel Hill)Torsten O. Nielsen(BC Cancer Agency)
Abstract
The expanded surrogate immunopanel of estrogen receptor, progesterone receptor, human HER-2, EGFR, and cytokeratin 5/6 provides a more specific definition of basal-like breast cancer that better predicts breast cancer survival.
Breast Cancer Treatment StudiesNonmelanoma Skin Cancer StudiesHER2/EGFR in Cancer ResearchBreast cancerTriple-negative breast cancerOncologyProgesterone receptorInternal medicineMedicineCytokeratinAnthracyclineTissue microarrayBasal (medicine)
MeSH terms
AdultAgedBreast NeoplasmsFemaleFollow-Up StudiesHumansImmunoenzyme TechniquesMiddle AgedNeoplasm InvasivenessPrognosisReceptors, EstrogenReceptors, ProgesteroneBiomarkers, TumorCohort StudiesIn Situ Hybridization, Fluorescence
Funding
- Sanofi
- Michael Smith Health Research BC
- National Cancer Institute
Citations
1,187
FWCI
38.23
field-weighted impact
References
41
Percentile
100%
vs. same field & year
Citations per year
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