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The Preclinical Phase of Alzheimer Disease
Archives of Neurology · 2000 · Vol. 57(6) · pp. 808–808
Merrill F. Elias✉(Boston University)Alexa BeiserPhilip A. WolfRhoda AuRoberta F. WhiteRalph B. D’Agostino
Abstract
The "preclinical phase" of detectable lowering of cognitive functioning precedes the appearance of pAD by many years. Measures of retention of information and abstract reasoning are among the strongest predictors of pAD when the interval between initial assessment and the development of pAD is long. Arch Neurol. 2000.
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsHealth, Environment, Cognitive AgingDementiaNeuropsychologyNeuropsychological testingCognitionNeuropsychological testPsychologyMedicineCognitive testDiseaseAudiology
MeSH terms
AgedAged, 80 and overAlzheimer DiseaseCognitionEducationHumansLearningMemoryNeuropsychological TestsProspective StudiesThinking
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References
Is semantic memory consistently impaired early in the course of Alzheimer's disease? Neuroanatomical and diagnostic implications
Neuropsychologia · 1995 · 639 citations
Clinical diagnosis of Alzheimer's disease
Neurology · 1984 · 27,910 citations
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