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Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease
Archives of Neurology · 2001 · Vol. 58(3) · pp. 397–405
Julie Morris✉(Alzheimer’s Disease Neuroimaging Initiative)Martha StorandtJ. Philip MillerDaniel W. McKeelJoseph L. PriceEugene H. RubinL Berg
Abstract
Individuals currently characterized as having MCI progress steadily to greater stages of dementia severity at rates dependent on the level of cognitive impairment at entry and they almost always have the neuropathologic features of AD. We conclude that MCI generally represents early-stage AD.
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsHealth, Environment, Cognitive AgingClinical Dementia RatingDementiaInternal medicineConfidence intervalAlzheimer's diseaseMedicineStage (stratigraphy)PsychologyProspective cohort studyCognitive impairment
MeSH terms
AgedAged, 80 and overAlzheimer DiseaseBrainCognition DisordersFemaleHumansLongitudinal StudiesMaleMiddle AgedPrognosisProspective StudiesSurvival AnalysisDisease Progression
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