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Brain reserve and dementia: a systematic review

Psychological Medicine · 2005 · Vol. 36(4) · pp. 441–454
Michael ValenzuelaPerminder S. Sachdev

Abstract

This study demonstrates robust evidence that complex patterns of mental activity in the early, mid- and late-life stages is associated with a significant reduction in dementia incidence. Randomized control trials based on brain-reserve principles are now required.

Dementia and Cognitive Impairment ResearchFunctional Brain Connectivity StudiesHealth, Environment, Cognitive AgingDementiaCognitive reserveContext (archaeology)Cochrane LibraryOdds ratioFrontotemporal dementiaMedicinePsychologyCohort studyEpidemiology

MeSH terms

BrainDementiaHumansLeisure ActivitiesPublic Health
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