review Open AccessTop 1% cited
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
Nature reviews. Cancer · 2006 · Vol. 6(1) · pp. 38–51
Saverio Minucci✉(European Institute of Oncology)Pier Giuseppe Pelicci(European Institute of Oncology)
Histone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsEpigenetics and DNA MethylationHistone deacetylaseEpigeneticsHistoneContext (archaeology)VorinostatHistone deacetylase inhibitorCarcinogenesisCancer researchComputational biologyCancer
MeSH terms
Histone DeacetylasesHumansNeoplasmsEpigenesis, GeneticHistone AcetyltransferasesHistone Deacetylase Inhibitors
Citations
2,190
FWCI
73.30
field-weighted impact
References
145
Percentile
100%
vs. same field & year
Citations per year
Cited by
Histone Deacetylase Inhibitors as Anticancer Drugs
International Journal of Molecular Sciences · 2017 · 1,159 citations
Anticancer activities of histone deacetylase inhibitors
Nature Reviews Drug Discovery · 2006 · 2,905 citations
HDAC family: What are the cancer relevant targets?
Cancer Letters · 2008 · 1,047 citations
Cellular senescence: when bad things happen to good cells
Nature Reviews Molecular Cell Biology · 2007 · 4,259 citations
The Epigenomics of Cancer
Cell · 2007 · 4,415 citations
Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy
Cancer Letters · 2008 · 425 citations
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
Nature Reviews Drug Discovery · 2014 · 1,501 citations
Histone deacetylase inhibitors: molecular mechanisms of action
Oncogene · 2007 · 1,533 citations
References
Histone-deacetylase inhibitors: novel drugs for the treatment of cancer
Nature Reviews Drug Discovery · 2002 · 1,513 citations
The language of covalent histone modifications
Nature · 2000 · 8,530 citations
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
The EMBO Journal · 2003 · 1,236 citations
The history of cancer epigenetics
Nature reviews. Cancer · 2004 · 2,348 citations
Acetylation: a regulatory modification to rival phosphorylation?
The EMBO Journal · 2000 · 1,150 citations
Stem cells, cancer, and cancer stem cells
Nature · 2001 · 9,682 citations
Class II histone deacetylases: versatile regulators
Trends in Genetics · 2003 · 655 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
