article Open AccessTop 1% cited
Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
Cell stem cell · 2010 · Vol. 7(5) · pp. 618–630
Luigi Warren✉(Boston Children's Hospital)Philip D. Manos(Harvard University)Tim Ahfeldt(Universität Hamburg)Yuin‐Han Loh(Harvard University)Hu Li(Harvard University)Frank H. Lau(Stowers Institute for Medical Research)Wataru Ebina(Boston Children's Hospital)Pankaj Kumar Mandal(Boston Children's Hospital)Zachary D. Smith(Broad Institute)Alexander Meissner(Harvard University)George Q. Daley(Dana-Farber/Boston Children's Cancer and Blood Disorders Center)Andrew S. Brack(Massachusetts General Hospital)James J. Collins(Harvard University)Chad A. Cowan(Harvard University)Thorsten M. Schlaeger(Dana-Farber Cancer Institute)Derrick J. Rossi(Boston Children's Hospital)
Pluripotent Stem Cells ResearchCRISPR and Genetic EngineeringRNA Interference and Gene DeliveryReprogrammingInduced pluripotent stem cellBiologyRegenerative medicineSomatic cellCellular differentiationCell biologyCell fate determinationComputational biologyDirected differentiation
MeSH terms
Cell DifferentiationCells, CulturedHumansRNA, MessengerCell LineageInduced Pluripotent Stem CellsCellular Reprogramming
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References
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Cell stem cell · 2009 · 1,785 citations
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Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells
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Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
Cell · 2006 · 26,294 citations
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
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