articleTop 1% cited
Prevention of Experimental Choroidal Neovascularization With Intravitreal Anti–Vascular Endothelial Growth Factor Antibody Fragment
Archives of Ophthalmology · 2002 · Vol. 120(3) · pp. 338–338
Magdalena G. Krzystolik✉(Massachusetts Eye and Ear Infirmary)
Abstract
This study provides the nonclinical proof of principle for ongoing clinical studies of intravitreally injected rhuFab VEGF in patients with neovascular age-related macular degeneration.
Retinal Diseases and TreatmentsRetinal Imaging and AnalysisRetinal and Optic ConditionsMedicineChoroidal neovascularizationOphthalmologyVascular endothelial growth factorFluorescein angiographyNeovascularizationVEGF receptorsAngiogenesisMacular degenerationVisual acuity
MeSH terms
AnimalsAntibodies, MonoclonalDisease Models, AnimalFluorescein AngiographyImmunoglobulin FragmentsInjectionsLymphokinesMacaca fascicularisRecombinant Fusion ProteinsSafetyUveitis, AnteriorVitreous BodyEndothelial Growth FactorsLaser CoagulationChoroidal Neovascularization
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588
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References
Inhibition of Vascular Endothelial Growth Factor Prevents Retinal Ischemia—Associated Iris Neovascularization in a Nonhuman Primate
Archives of Ophthalmology · 1996 · 631 citations
Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor
American Journal of Ophthalmology · 1996 · 621 citations
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