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Inhibition of Vascular Endothelial Growth Factor Prevents Retinal Ischemia—Associated Iris Neovascularization in a Nonhuman Primate

Archives of Ophthalmology · 1996 · Vol. 114(1) · pp. 66–66
Anthony P. Adamis

Abstract

These data demonstrate that VEGF is required for iris neovascularization in an adult nonhuman primate eye. The inhibition of VEGF is a new potential therapeutic strategy for the treatment of ocular neovascularization.

Glaucoma and retinal disordersRetinal Diseases and TreatmentsIntraocular Surgery and LensesNeovascularizationVascular endothelial growth factorRetinalVascular endothelial growth factor ARetinaMedicineOphthalmologyAngiogenesisBiologyPathology

MeSH terms

Placenta Growth FactorAnimalsAntibodies, MonoclonalCapillary PermeabilityFluorescein AngiographyIrisIschemiaLymphokinesMacaca fascicularisNeovascularization, PathologicPregnancy ProteinsRandom AllocationRetinaRetinal Vein OcclusionRNA, Messenger
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