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Open-Label Phase III Trial of Panitumumab Plus Best Supportive Care Compared With Best Supportive Care Alone in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer
Journal of Clinical Oncology · 2007 · Vol. 25(13) · pp. 1658–1664
Eric Van Cutsem✉(Vrije Universiteit Brussel)Marc Peeters(Vrije Universiteit Brussel)Salvatore Siena(Cabrini Hospital)Yves Humblet(Ghent University Hospital)Alain Hendlisz(Cabrini Hospital)Bart Neyns(Ghent University Hospital)Jean-Luc Canon(Ghent University Hospital)Jean–Luc Van Laethem(Vrije Universiteit Brussel)Joan Maurel(Vrije Universiteit Brussel)Gary Richardson(Vrije Universiteit Brussel)Michael Wolf(Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda)Rafael G. Amado(Vrije Universiteit Brussel)
Abstract
Panitumumab significantly improved PFS with manageable toxicity in patients with chemorefractory colorectal cancer.
Colorectal Cancer Treatments and StudiesColorectal and Anal CarcinomasGastric Cancer Management and OutcomesPanitumumabMedicineInternal medicineColorectal cancerHazard ratioResponse Evaluation Criteria in Solid TumorsChemotherapyClinical endpointOncologyProgressive disease
MeSH terms
PanitumumabAgedAntibodies, MonoclonalAntineoplastic AgentsFemaleHumansImmunohistochemistryMaleMiddle AgedNeoplasm MetastasisColorectal NeoplasmsDisease-Free SurvivalErbB Receptors
Funding
- Amgen
Citations
1,996
FWCI
84.65
field-weighted impact
References
34
Percentile
100%
vs. same field & year
Citations per year
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