article Open AccessTop 1% cited
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
New England Journal of Medicine · 2004 · Vol. 350(23) · pp. 2335–2342
Herbert I. Hurwitz✉(Duke University)Louis FehrenbacherWilliam NovotnyThomas H. CartwrightJohn D. Hainsworth(Sarah Cannon)W. HeimJordan Berlin(Vanderbilt University)Ari David Baron(California Pacific Medical Center)S. GriffingEric HolmgrenNapoleone FerraraGwen FyfeBeth RogersRobert W. RossFairooz F. Kabbinavar(University of California, Los Angeles)
Abstract
The addition of bevacizumab to fluorouracil-based combination chemotherapy results in statistically significant and clinically meaningful improvement in survival among patients with metastatic colorectal cancer.
Colorectal Cancer Treatments and StudiesCancer Treatment and PharmacologyHepatocellular Carcinoma Treatment and PrognosisMedicineIrinotecanBevacizumabFluorouracilColorectal cancerOncologyInternal medicineChemotherapyCancer
MeSH terms
BevacizumabIrinotecanAntibodies, MonoclonalAntineoplastic Combined Chemotherapy ProtocolsCamptothecinLeucovorinFemaleFluorouracilHumansMaleMiddle AgedNeoplasm MetastasisQuality of LifeColorectal NeoplasmsSurvival Analysis
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References
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