article Open AccessTop 10% cited
The CD28 Signaling Pathway Regulates Glucose Metabolism
Immunity · 2002 · Vol. 16(6) · pp. 769–777
Kenneth A. Frauwirth(Cancer Research Institute)James L. Riley(Cancer Research Institute)Marian H. Harris(Cancer Research Institute)Richard V. Parry(University of Pennsylvania)Jeffrey C. Rathmell(University of Pennsylvania)David R. Plas(University of Pennsylvania)Rebecca Elstrom(University of Pennsylvania)Carl H. June(Cancer Research Institute)Craig B. Thompson✉(Cancer Research Institute)
Immune Cell Function and InteractionT-cell and B-cell ImmunologyCancer-related molecular mechanisms researchCD28GlycolysisBiologyCell biologyPI3K/AKT/mTOR pathwayPhosphatidylinositolSignal transductionT cellProtein kinase BCarbohydrate metabolism
MeSH terms
Adenosine DiphosphateBinding SitesCell LineGlucoseGlycolysisHomeostasisHumansLymphocyte ActivationMonosaccharide Transport ProteinsProto-Oncogene ProteinsSpectrometry, FluorescenceSignal TransductionProtein Serine-Threonine KinasesProtein Structure, SecondaryCD28 Antigens
Citations
1,417
FWCI
6.35
field-weighted impact
References
56
Percentile
97%
vs. same field & year
Citations per year
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References
PTEN: Life as a Tumor Suppressor
Experimental Cell Research · 2001 · 679 citations
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
The Journal of Experimental Medicine · 1995 · 2,186 citations
The insulin receptor: structure, function, and signaling
American Journal of Physiology-Cell Physiology · 1994 · 453 citations
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