article Open AccessTop 1% cited
Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
Immunity · 2011 · Vol. 36(1) · pp. 68–78
Gerritje J. W. van der Windt✉(Trudeau Institute)Bart Everts(Trudeau Institute)Chih‐Hao Chang(Trudeau Institute)Jonathan D. Curtis(Trudeau Institute)Tori C. Freitas(Trudeau Institute)Eyal Amiel(Trudeau Institute)Edward J. Pearce(Trudeau Institute)Erika L. Pearce(Trudeau Institute)
Immune Cell Function and InteractionT-cell and B-cell ImmunologyImmune Response and InflammationBiologyMitochondrial biogenesisCell biologyCD8MitochondrionCytotoxic T cellEffectorOxidative phosphorylationInterleukin 15Immunology
MeSH terms
AnimalsCarnitine O-PalmitoyltransferaseFatty AcidsFlow CytometryImmunologic MemoryMice, Inbred C57BLMitochondriaModels, BiologicalOxidation-ReductionCD8-Positive T-LymphocytesCell RespirationInterleukin-15MiceReal-Time Polymerase Chain Reaction
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References
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
Nature Immunology · 2003 · 1,806 citations
The CD28 Signaling Pathway Regulates Glucose Metabolism
Immunity · 2002 · 1,417 citations
Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice
The Journal of Experimental Medicine · 2000 · 1,584 citations
Cytokine Stimulation Promotes Glucose Uptake via Phosphatidylinositol-3 Kinase/Akt Regulation of Glut1 Activity and Trafficking
Molecular Biology of the Cell · 2007 · 567 citations
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