reviewTop 1% cited

Signaling through the JAK/STAT pathway, recent advances and future challenges

Gene · 2002 · Vol. 285(1-2) · pp. 1–24

Tatiana Kisseleva(Columbia University)Samita Bhattacharya(Columbia University)Jutta Braunstein(Columbia University)Chris Schindler✉(Columbia University)

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Cytokine Signaling Pathways and Interactions Protein Tyrosine Phosphatases Cancer Mechanisms and TherapyBiologystatJAK-STAT signaling pathwayJanus kinaseCell biologySignal transductionSTAT proteinSTAT6Transcription factorFunction (biology)

MeSH terms

AnimalsDNA-Binding ProteinsHumansPhosphorylationProtein-Tyrosine KinasesSignal TransductionTrans-ActivatorsCytokinesReceptors, CytokineEvolution, Molecular

Citations

1,153

FWCI

22.68

field-weighted impact

References

270

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100%

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Citations per year

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References

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Serine phosphorylation of STATs

Oncogene · 2000 · 887 citations

Leptomycin B Inhibition of Signal-Mediated Nuclear Export by Direct Binding to CRM1

Experimental Cell Research · 1998 · 820 citations

The role of nitric oxide in innate immunity

Immunological Reviews · 2000 · 658 citations

STATs in oncogenesis

Oncogene · 2000 · 1,728 citations

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

Immunity · 1996 · 1,621 citations

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

Immunity · 2000 · 2,788 citations

JAKS AND STATS: Biological Implications

Annual Review of Immunology · 1998 · 1,808 citations

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