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Leptomycin B Inhibition of Signal-Mediated Nuclear Export by Direct Binding to CRM1

Experimental Cell Research · 1998 · Vol. 242(2) · pp. 540–547

N. Kudo(The University of Tokyo)Barbara Wolff(Novartis (Austria))Toshihiro Sekimoto(Osaka University)Erwin Schreiner(Novartis (Austria))Yoshihiro Yoneda(Osaka University)Mitsuhiro Yanagida(Kyoto University)Sueharu Horinouchi(The University of Tokyo)Minoru Yoshida✉(The University of Tokyo)

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Nuclear Structure and Function RNA Research and Splicing Biotin and Related StudiesNuclear export signalBiologyNuclear transportCytoplasmCell nucleusNuclear proteinNucleoplasmNuclear localization sequenceCell biologyKaryopherin

MeSH terms

Exportin 1 ProteinBiological Transport, ActiveCarrier ProteinsCell NucleusCytoplasmFatty Acids, UnsaturatedHeLa CellsHumansNuclear ProteinsProtein BindingRecombinant ProteinsSchizosaccharomycesSignal TransductionGene Products, revReceptors, Cytoplasmic and Nuclear

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