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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

Nature Cell Biology · 2013 · Vol. 16(1) · pp. 55–65
Zhenyu CaiSiriporn JitkaewJie ZhaoHsueh‐Cheng ChiangSwati ChoksiJie LiuYvona WardLing-Gang WuZheng Gang Liu
Cell death mechanisms and regulationTrace Elements in HealthNecroptosisCell biologyBiologyPhosphorylationProgrammed cell deathCytosolTumor necrosis factor alphaApoptosisBiochemistryImmunology

MeSH terms

AnimalsCalciumCell MembraneHumansImidazolesIndolesNecrosisProtein KinasesTumor Necrosis Factor-alphaApoptosisProtein Serine-Threonine KinasesProtein Structure, TertiaryHT29 CellsJurkat CellsProtein Transport
Citations
1,307
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36.48
field-weighted impact
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33
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100%
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References
Necroptosis as an alternative form of programmed cell death
Current Opinion in Cell Biology · 2010 · 779 citations
Apoptosis control by death and decoy receptors
Current Opinion in Cell Biology · 1999 · 1,292 citations
Immunity, Inflammation, and Cancer
Cell · 2010 · 10,570 citations
Molecular mechanisms of necroptosis: an ordered cellular explosion
Nature Reviews Molecular Cell Biology · 2010 · 2,327 citations
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