reviewTop 1% cited
Apo2L/TRAIL and its death and decoy receptors
Cell Death and Differentiation · 2003 · Vol. 10(1) · pp. 66–75
Heidi Leblanc✉Avi Ashkenazi(Genentech)
Cell death mechanisms and regulationPhagocytosis and Immune RegulationNF-κB Signaling PathwaysDecoyReceptorApoptosisTumor necrosis factor alphaCell biologySignal transductionBiologyProgrammed cell deathLigand (biochemistry)Cancer cell
MeSH terms
AnimalsEukaryotic CellsHumansMembrane GlycoproteinsPhylogenyTumor Necrosis Factor-alphaSignal TransductionApoptosisProtein Structure, TertiaryReceptors, Tumor Necrosis FactorProto-Oncogene Proteins c-bcl-2Apoptosis Regulatory ProteinsTNF-Related Apoptosis-Inducing Ligand
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848
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References
Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo
Nature Medicine · 1999 · 2,493 citations
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.
The EMBO Journal · 1995 · 2,138 citations
Two CD95 (APO-1/Fas) signaling pathways
The EMBO Journal · 1998 · 2,997 citations
The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues
Molecular Cell · 2000 · 1,468 citations
Apoptosis control by death and decoy receptors
Current Opinion in Cell Biology · 1999 · 1,292 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL
The EMBO Journal · 1997 · 1,128 citations
Safety and antitumor activity of recombinant soluble Apo2 ligand
Journal of Clinical Investigation · 1999 · 2,210 citations
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