reviewTop 1% cited

TRAIL and apoptosis induction by TNF-family death receptors

Oncogene · 2003 · Vol. 22(53) · pp. 8628–8633

Shulin Wang✉(Howard Hughes Medical Institute)Wafik S. El‐Deiry(Howard Hughes Medical Institute)

Cell death mechanisms and regulation NF-κB Signaling Pathways Cancer-related Molecular PathwaysTumor necrosis factor alphaApoptosisBiologyReceptorCancer researchProgrammed cell deathEffectorSignal transductionCancer cellCancer

MeSH terms

AnimalsHumansMembrane GlycoproteinsNeoplasmsTumor Necrosis Factor-alphaSignal TransductionApoptosisReceptors, Tumor Necrosis FactorApoptosis Regulatory ProteinsReceptors, TNF-Related Apoptosis-Inducing LigandTNF-Related Apoptosis-Inducing Ligand

Citations

874

FWCI

13.10

field-weighted impact

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99%

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Citations per year

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References

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Nature Medicine · 1999 · 2,493 citations

Two CD95 (APO-1/Fas) signaling pathways

The EMBO Journal · 1998 · 2,997 citations

Apo2L/TRAIL and its death and decoy receptors

Cell Death and Differentiation · 2003 · 848 citations

Safety and antitumor activity of recombinant soluble Apo2 ligand

Journal of Clinical Investigation · 1999 · 2,210 citations

Identification and characterization of a new member of the TNF family that induces apoptosis

Immunity · 1995 · 2,891 citations

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