article Open AccessTop 1% cited

Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Current Biology · 2004 · Vol. 14(14) · pp. 1296–1302

Dos D. Sarbassov(Whitehead Institute for Biomedical Research)Siraj M. Ali(Whitehead Institute for Biomedical Research)Do‐Hyung Kim(Whitehead Institute for Biomedical Research)David A. Guertin(Whitehead Institute for Biomedical Research)Robert Latek(Whitehead Institute for Biomedical Research)Hediye Erdjument‐Bromage(Memorial Sloan Kettering Cancer Center)Paul Tempst(Memorial Sloan Kettering Cancer Center)David M. Sabatini✉(Whitehead Institute for Biomedical Research)

View via DOI Full-text PDF

PI3K/AKT/mTOR signaling in cancer Coagulation, Bradykinin, Polyphosphates, and Angioedema Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR pathwayBiologyCell growthCell biologyMechanistic target of rapamycinSignal transductionGenetics

MeSH terms

Regulatory-Associated Protein of mTORRapamycin-Insensitive Companion of mTOR ProteinActinsAmino Acid SequenceAnimalsCarrier ProteinsCytoskeletonDrosophilaElectrophoresis, Polyacrylamide GelFluorescent Antibody TechniqueHeLa CellsHumansMolecular Sequence DataPhosphorylationPrecipitin Tests

Citations

2,646

FWCI

28.34

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)