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Caco-2 monolayers in experimental and theoretical predictions of drug transport1PII of original article: S0169-409X(96)00415-2. The article was originally published in Advanced Drug Delivery Reviews 22 (1996) 67–84.1

Advanced Drug Delivery Reviews · 2001 · Vol. 46(1-3) · pp. 27–43

Per Artursson✉(Uppsala University)Katrin Palm(Uppsala University)Kristina Luthman(Uppsala University)

Drug Solubulity and Delivery Systems Advanced Drug Delivery Systems Drug Transport and Resistance MechanismsMonolayerDrugAbsorption (acoustics)In vivoDrug deliveryCaco-2ChemistryPharmacologyMedicineMaterials science

MeSH terms

Biological Transport, ActiveChemistry, PhysicalPharmaceutical PreparationsHumansCaco-2 CellsChemical Phenomena

Funding

Vetenskapsrådet

Citations

1,524

FWCI

35.93

field-weighted impact

References

110

Percentile

100%

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Citations per year

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References

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Pharmaceutical Research · 1995 · 5,270 citations

Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal Mucosa

Pharmaceutical Research · 1990 · 579 citations

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Gastroenterology · 1989 · 2,193 citations

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Biochemical and Biophysical Research Communications · 1991 · 1,852 citations

Atom/Fragment Contribution Method for Estimating Octanol–Water Partition Coefficients

Journal of Pharmaceutical Sciences · 1995 · 860 citations

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

Journal of Pharmaceutical Sciences · 1990 · 833 citations

Occludin: a novel integral membrane protein localizing at tight junctions.

The Journal of Cell Biology · 1993 · 2,521 citations

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