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A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Pharmaceutical Research · 1995 · Vol. 12(3) · pp. 413–420

Gordon L. Amidon✉(University of Michigan–Ann Arbor)Hans Lennernäs(Uppsala University)Vinod P. Shah(Parenteral Drug Association)John R. Crison(Therapeutics Systems Research Laboratories (United States))

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Drug Solubulity and Delivery Systems Crystallization and Solubility Studies Analytical Methods in PharmaceuticalsBiopharmaceutics Classification SystemSolubilityDissolutionBioavailabilityBiopharmaceuticsDrugChemistryIn vivoDissolution testingDosage form

MeSH terms

Biological AvailabilityCimetidinePharmaceutical PreparationsGastric EmptyingJejunumMathematicsModels, TheoreticalPermeabilityPiroxicamSolubilityIn Vitro Techniques

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5,270

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27.13

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