review Open AccessTop 1% cited
Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
Molecular Cell · 2012 · Vol. 47(4) · pp. 497–510
DNA Repair MechanismsCarcinogens and Genotoxicity AssessmentPARP inhibition in cancer therapyBiologyNon-homologous end joiningGenome instabilityDNA repairHomologous recombinationGeneticsDNA damageCarcinogenesisCell biologyGenome
MeSH terms
AnimalsCell CycleDNA RepairHumansRecombination, GeneticGenomic InstabilityDNA Breaks, Double-Stranded
Citations
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References
DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139
Journal of Biological Chemistry · 1998 · 5,347 citations
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
Nature Structural & Molecular Biology · 2010 · 1,017 citations
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