letter Open AccessTop 1% cited
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
Nature Structural & Molecular Biology · 2010 · Vol. 17(6) · pp. 688–695
Peter Bouwman✉(The Netherlands Cancer Institute)Amal Aly(Rutgers Cancer Institute of New Jersey)José Miguel Escandell(CRUK/MRC Oxford Institute for Radiation Oncology)Mark Pieterse(Oncode Institute)Jiřina Bártková(Danish Cancer Society)Hanneke van der Gulden(Oncode Institute)Sanne Hiddingh(The Netherlands Cancer Institute)Maria Thanasoula(CRUK/MRC Oxford Institute for Radiation Oncology)Atul Kulkarni(Cancer Institute of Florida)Qifeng Yang(Rutgers Cancer Institute of New Jersey)Bruce G. Haffty(Rutgers Cancer Institute of New Jersey)Johanna Tommiska(Helsinki University Hospital)Carl Blomqvist(Helsinki University Hospital)Ronny Drapkin(Dana-Farber Cancer Institute)David J. Adams(Wellcome Sanger Institute)Heli Nevanlinna(Helsinki University Hospital)Jiří Bártek(Palacký University Olomouc)Madalena Tarsounas(CRUK/MRC Oxford Institute for Radiation Oncology)Shridar Ganesan(Rutgers Cancer Institute of New Jersey)Jos Jonkers(The Netherlands Cancer Institute)
DNA Repair MechanismsPARP inhibition in cancer therapyGenomics and Chromatin DynamicsCancer researchGenome instabilityHomologous recombinationDNA damageBRCA2 ProteinCell cycle checkpointBiologyMutationDNA repairCHEK1
MeSH terms
Tumor Suppressor p53-Binding Protein 1AnimalsBreast NeoplasmsCell CycleChromosomal Proteins, Non-HistoneDNA DamageDNA RepairDNA-Binding ProteinsFemaleHumansMutationTumor Cells, CulturedMutagenesis, InsertionalGene DeletionMice, Knockout
Funding
- U.S. Department of Defense
- Breast Cancer Research Foundation
- Helsingin ja Uudenmaan Sairaanhoitopiiri
- Wellcome Trust
- Cancer Research UK
- Breast Cancer Campaign
- National Research Foundation
- Danmarks Grundforskningsfond
- National Cancer Institute
Citations
1,017
FWCI
30.56
field-weighted impact
References
57
Percentile
100%
vs. same field & year
Citations per year
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References
Regulation of the G2/M transition by p53
Oncogene · 2001 · 1,554 citations
Repeated observation of breast tumor subtypes in independent gene expression data sets
Proceedings of the National Academy of Sciences · 2003 · 5,398 citations
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