reviewTop 1% cited
Bcl-2 family proteins
Oncogene · 1998 · Vol. 17(25) · pp. 3225–3236
John C. Reed✉(Sanford Burnham Prebys Medical Discovery Institute)
Cell death mechanisms and regulationProtein Kinase Regulation and GTPase SignalingCancer-related Molecular PathwaysBiologyBcl-2 familyProgrammed cell deathApoptosisCell biologyCarcinogenesisProtein familyFunction (biology)CellCancer research
MeSH terms
AnimalsBiological TransportCell MembraneCell Membrane PermeabilityMultigene FamilyHumansMitochondriaProtein BindingSignal TransductionCell DeathApoptosisPorinsProto-Oncogene Proteins c-bcl-2Dimerization
Citations
1,055
FWCI
31.93
field-weighted impact
References
65
Percentile
100%
vs. same field & year
Citations per year
Cited by
Control of apoptosis by Rel/NF-κB transcription factors
Oncogene · 1999 · 1,198 citations
BCL-2 family members and the mitochondria in apoptosis
Genes & Development · 1999 · 3,645 citations
JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
Molecular Cell · 2008 · 1,299 citations
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
Cell Death and Differentiation · 2000 · 1,027 citations
Phosphorylation of Bcl2 and regulation of apoptosis
Leukemia · 2001 · 487 citations
Molecular mechanisms of drug resistance
The Journal of Pathology · 2005 · 1,646 citations
Apoptosis in cancer
Carcinogenesis · 2000 · 1,870 citations
Escaping Cell Death: Survival Proteins in Cancer
Experimental Cell Research · 1999 · 611 citations
References
Two CD95 (APO-1/Fas) signaling pathways
The EMBO Journal · 1998 · 2,997 citations
Bcl-2 and the regulation of programmed cell death
The Journal of Cell Biology · 1994 · 2,332 citations
Mitochondria and Apoptosis
Science · 1998 · 8,971 citations
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · 7,227 citations
Movement of Bax from the Cytosol to Mitochondria during Apoptosis
The Journal of Cell Biology · 1997 · 1,800 citations
Related articles
BCL-2 family proteins: changing partners in the dance towards death
Cell Death and Differentiation · 2017 · 1,530 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.