review Open AccessTop 1% cited
Rapamycin: One Drug, Many Effects
Cell Metabolism · 2014 · Vol. 19(3) · pp. 373–379
PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex ResearchProtein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR pathwayMechanistic target of rapamycinRegulatorSirolimusDrugMechanism of actionDiscovery and development of mTOR inhibitorsDrug developmentCell growthBiology
MeSH terms
AgingDrug Therapy, CombinationHumansLongevityLung DiseasesMetabolic DiseasesNeoplasmsNervous System DiseasesSignal TransductionSirolimusTOR Serine-Threonine Kinases
Funding
- Foundation for the National Institutes of Health
- Tuberous Sclerosis Alliance
- LAM Foundation
Citations
1,265
FWCI
21.35
field-weighted impact
References
45
Percentile
100%
vs. same field & year
Citations per year
Cited by
mTOR: a pharmacologic target for autophagy regulation
Journal of Clinical Investigation · 2015 · 2,079 citations
References
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
Trends in Biochemical Sciences · 2011 · 1,790 citations
Molecular mechanisms of mTOR-mediated translational control
Nature Reviews Molecular Cell Biology · 2009 · 2,525 citations
mTOR Signaling in Growth Control and Disease
Cell · 2012 · 8,373 citations
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