reviewTop 1% cited
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
Trends in Biochemical Sciences · 2011 · Vol. 36(6) · pp. 320–328
Michelle C. Mendoza(Harvard University)Ekrem Emrah Er(Harvard University)John Blenis✉(Harvard University)
PI3K/AKT/mTOR signaling in cancerMelanoma and MAPK PathwaysProtein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR pathwayMAPK/ERK pathwayCell biologyKinaseSignal transductionBiologyExtracellularPhosphatidylinositolMotilityRPTOR
MeSH terms
HumansSignal Transductionras ProteinsExtracellular Signal-Regulated MAP KinasesPhosphatidylinositol 3-KinaseTOR Serine-Threonine Kinases
Funding
- LAM Foundation
- Susan G. Komen
Citations
1,790
FWCI
26.75
field-weighted impact
References
105
Percentile
100%
vs. same field & year
Citations per year
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Oncogene · 2007 · 1,098 citations
AKT/PKB Signaling: Navigating Downstream
Cell · 2007 · 6,033 citations
FOXO transcription factors at the interface between longevity and tumor suppression
Oncogene · 2005 · 1,297 citations
Cell Signaling by Receptor Tyrosine Kinases
Cell · 2010 · 7,809 citations
MAP kinase signalling pathways in cancer
Oncogene · 2007 · 2,984 citations
Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K
Cancer Cell · 2010 · 1,226 citations
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
Genes & Development · 2000 · 1,414 citations
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