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Regulation of Lifespan in Drosophila by Modulation of Genes in the TOR Signaling Pathway

Current Biology · 2004 · Vol. 14(10) · pp. 885–890

Pankaj Kapahi✉(California Institute of Technology)Brian M. Zid(California Institute of Technology)Tony Harper(California Institute of Technology)Daniel Koslover(California Institute of Technology)Viveca Sapin(California Institute of Technology)Seymour Benzer(California Institute of Technology)

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Genetics, Aging, and Longevity in Model Organisms Circadian rhythm and melatonin CRISPR and Genetic EngineeringBiologyScopusGeneInsulin receptorGeneticsDrosophila (subgenus)Candidate geneAgeingInsulinInsulin resistance

MeSH terms

Tuberous Sclerosis Complex 1 ProteinTuberous Sclerosis Complex 2 ProteinAdipose TissueAnimalsDrosophilaEatingGene Expression RegulationLongevityProtein KinasesProteinsRepressor ProteinsTime FactorsSignal TransductionPhosphatidylinositol 3-KinasesRibosomal Protein S6 Kinases

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